At the start of the movie, Banner is watching TV, and on TV a man gets slapped across the face. This is a young Bill Bixby who went on to play Banner in The Incredible Hulk TV Series.

The news clip mentioned a campus magazine reporter called Jack McGee who had witnessed the Hulk assault in the grounds. This is a nod to the TV series where David Banner was pursued by an investigative reporter of the same name.

In the film, a serum is mentioned as being created during World War II. This is a reference to the super soldier serum that created Captain America.

The green cross, projected onto Dr. Banner's forehead, is exactly the same as the one from the original TV series.

When Bruce is browsing through Betty Ross's files, we can briefly glimpse a file name with something to the effect of "animal webbing in human subjects". A nod to Spider-Man, perhaps?

During the creation of Abomination, the doctor performing the procedure gets some infected blood in a cut on his head and his head starts to pulsate. This looks like it will be a set up for the Leader to appear. The Leader is a character with enhanced brain power but ordinary strength.

Stan Lee (Stanley Martin Lieber), the original creator of this comic book hero, has his usual cameo role in this movie. He's the guy who drinks the gamma contaminated soda from the fridge.

The security guard Banner manages to bribe with pizza is Lou Ferrigno, who played the Hulk in the TV series. Ferrigno also had a cameo as a security guard in The Hulk (2003).

Not only is STARK enterprises used, i.e. Iron Man, but Nick Fury, another Marvel hero, is mentioned on a piece of paper. Nick Fury is played by Samuel L. Jackson in Iron Man, so maybe another hint at Avengers, as Nick Fury is an agent of SHIELD.

In the scene in the hotel Betty throws Bruce a pair of large purple shorts she has bought. This is a nod to the comic where the Hulk always wore large purple shorts.

When Bruce receives Betty's necklace in the mail, the package is addressed to David B. The name David Banner was used in the The Incredible Hulk TV series when it was decided the name Bruce would lead people to think the character was homosexual.

Aside from Lou Ferrigno appearing in the film, there are other nods to the TV series such as the piano song about 1/4 of the way through the film(when Dr Banner is walking the streets) and when Dr Banner and Dr Ross steal the truck, its a 70's model F-150 which Dr Banner also drove in the TV series, albeit a different colored one.

Bruce Banner is inexplicably called Bob for several issues of The Hulk comic books. This was a mistake on the part of Stan Lee who had a hard time remembering his characters names, presumably because he drew several superhero comic book series at the same time. It was later revealed that Bruce Banner's full name is Robert Bruce Banner.

In addition to the large purple stretchy shorts already mentioned, Betty came back with a lumberjack style shirt, which she put on herself - a nod to the TV series where David Banner often wore one of these ahead of the rip scenes.

Near the end of the film, Bruce Banner falls from an airplane, transforming into the Hulk just before hitting the ground. This is a reversal of a scene from the TV movie "The Death of the Incredible Hulk" in which the Hulk falls from an airplane, transforming back into Banner just before hitting the ground.