Continuity: Throughout the entire film the tattoo on George Clooney's neck moves position and changes shape.

Revealing: When George Clooney is talking to Juliette Lewis towards the end of the film, it is painfully obvious that his tattoo has been smudged.

Continuity: When Jacob gets bitten, he is thrown across the room by Sex Machine. If you look closely as he's flying through the air, you can see the wound on his arm has disappeared.

Continuity: In the final battle, Jacob turns into a vampire and bites Scott, when Scott hits Jacob with the holy water bomb, Jacob backs away from Scott, when Jacob removes his mouth from Scott's neck, there is no blood on it, two cuts later, there is blood on Scott's neck.

Continuity: After Sex Machine bites the trucker, the trucker throws Sex Machine through the door or wall, letting in all the vampires. But later, Seth needs Carlos to break the door down in order to let in the sunlight, killing all the vampires. What happened to the big hole made by Sex Machine when he was thrown outside? Why didn't that provide the sunlight needed to kill the vampires?

Continuity: When Sex Machine turns into a vampire, he covers his mouth so he doesn't show his fangs. When his hand changes, he tries to cover it up with his other hand. Watch this other hand. In the shot where THAT hand changes, it is in a different position from before.

Continuity: In the shot where we see the bar (for the very first time) they are going to, you can see the background is flat, kind of like the building is on a flat area of land with nothing behind it. At the end of the film we see not only a giant ditch but also the trucks from over the years piled up behind the bar.

Factual error: The Abilene, Texas courthouse should read Taylor County Courthouse, being that Abilene is the county seat of Taylor County, Texas. All Texas courthouses are named by the county they are in.

Continuity: During Santanico Pandemonium's routine, two dancers take the snake away so she can step forward. As they take the snake off, the second dancer is holding only a couple feet of the snake's tail, but in the next shot, the second dancer is holding the entire snake.

Continuity: At one point the RV is going down a rough, bumpy road and inside Seth and Richie are talking and everything is perfectly still.

Plot hole: When Scott is being sucked by the horde of vampires, Kate shoots him. This results in a big explosion. Scott may have had holy water in balloons strapped to his body, but the bullet fired off by Kate sure could not have triggered the explosion.

Continuity: During the scene when Seth questions why the bartender will not serve him, several camera shots go to the band on stage You don't even have to watch carefully to know the band, especially the drummer, are not playing their instruments and/or their miming is way off.

Continuity: In the hotel when the manager comes through the door, in the first shot the door is open, but the next time the door is closed.

Continuity: While Seth is talking to Carlos about the loss of his brother and Kate's family, Kate turns around to survey the damage. Two quick cuts later and she's facing exactly as she was before, down to the facial expression.

Continuity: When Seth introduces Gloria to Mr. .44, the gun is level and pointed at the door. Cut to over Seth's shoulder and the gun is pointed at the ceiling.

Plot hole: When Seth's piledriver gives out during the climactic fight, there are many vampires in the background politely keeping their distance while he tries to restart it. Similarly, they ignore him while both his hands are occupied with Sex Machine's whip, even though vampires are running around behind him to no apparent goal.

Continuity: When the bats fly in through the shattered window, Seth and the two kids run into the hallway that leads to the store room. In one shot you see how the bats overtake the trio. In the reverse shot, Seth and the two kids are still ahead of the bats.

Revealing: Shortly after passing the border Seth is talking to Jacob who's supposed to be driving. But the reflection in his glasses shows that they don't move.

Continuity: When it shows a shot from the front of Seth, Kate and Scott running from the bats, some bats catch up with them and fly past them. But in the next shot from the back of them, no bats have flown past.

Continuity: Frost gets green blood all over his hand after holding the vampires heart, but this disappears while they are fighting the four women. After the fight finishes, the blood returns.