After the boy in the green baseball cap gets bitten by Dennis for the 1st time, he tells his father "To make a sign or something." Later, in the "Pancakes" scene, look by the swing and you'll see a sign that says "Do Not Sit Next To Dennis."

The 'pancakes' scene was completely rewritten when auditions for Dennis were being held. Writer Eli Roth rewrote the whole scene when black-belt kid Matthew Helms amazed Eli with his karate moves in the audition.

At the end of the movie, the trailer truck is delivering Down Home spring water, in reference to a company who produced the movie, Down Home entertainment.

The Director Eli Roth actually had a flesh eating virus when he was in either Greenland or Iceland and that's what inspired him to do this movie.

The scene where Paul runs into the deer in the jeep, this in reference to the fact that the movie was made in association with Deer Path Films.