Factual error: In the game at Pittsburgh, when Ruth hits three home runs, the first two were hit off Guy Bush. When he comes to bat the last time, Guy Bush is still pitching. This was not the case. Red Lucas was the pitcher, and he gave up Ruth's last home run.

Factual error: With the Boston Red Sox, Babe Ruth is seen developing a friendship with Joe Dugan. Dugan didn't sign with the BoSox until well after Ruth was sold to the Yankees.

Factual error: All of the ballpark scenes (sans Fenway Park in Boston) were obviously shot at Wrigley Field in Chicago.

Continuity: There is a scene where Goodman is in the establishment where his future wife is working. There is a shot where it shows his beer glass with about 2 inches of head on it. The angle changes and in a matter of seconds, the head on the beer is gone.